Experimental Trauma Models: An Update

Computer Game Play Reduces Intrusive Memories of Experimental Trauma via Reconsolidation-Update Mechanisms

Memory of a traumatic event becomes consolidated within hours. Intrusive memories can then flash back repeatedly into the mind's eye and cause distress. We investigated whether reconsolidation-the process during which memories become malleable when recalled-can be blocked using a cognitive task and whether such an approach can reduce these unbidden intrusions. We predicted that reconsolidation ...

Numerical modeling of primary thoracic trauma because of blast

  Purpose: Since explosive blasts continue to cause casualties in both civil and military environments, there is a need for an understanding of the mechanisms of blast trauma at the human organ level, plus a more detailed predictive methodology. The primary goal of this research was to develop a finite element model capable of predicting primary blast injury to the lung so as to assist in the d...

Effect of Oleuropein on Tissue Myeloperoxidase Activity in Experimental Spinal Cord Trauma

Background: Neutrophil infiltration plays an important role in inflammatory reactions following spinal cord injury (SCI) and these cells cause substantial secondary tissue damage. The purpose of this study was to determine the effect of oleuropein (OE) on myeloperoxidase (MPO) activity as an index of neutrophil infiltration. Methods: Rats were randomly divided into four groups of 7 rats each as...

Molecular mechanisms underlying gallic acid effects against cardiovascular diseases: An update review

Objective: The prevalence of cardiovascular diseases (CVDs) is growing. CVDs are the major cause of mortality and have become one of the most important health challenges in developing countries. Gallic acid (GA) is a natural phytochemical which has been widely used against multiple conditions. The present review was designed to evaluate molecular mechanisms underlying the prote...

An update on current concepts of the epidemiology of bovine Pestivirus infection in cattle